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(2010), although the use of a LC supplement (4 g/day) for 4 months did not significantly improve primary outcomes, such as lean mass and fatigue, a positive impact on secondary indicators such as the Glasgow Prognostic Score and ECOG (Eastern Cooperative Oncology Group) performance status was reported

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Some patients and clinicians prematurely conclude the medication is ineffective before reaching therapeutic doses of 10-15 mg weekly

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However, this benefit was not sustained, with no significant differences observed at 12, 24, and 48 hours, consistent with the findings of Furat et al