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The 2019 BPCIA framework was written before this clinical category was as developed as it is today, and the PCAC review process has not yet moved these molecules onto the 503A Bulks List

10.1016/j.nutres.2023.10.003 150 ZhangP

J.EscobarR.SchachtA.et al

That is why patients experience not only anemia, but also low vitality, poor growth, reduced exercise tolerance, organ stress, and diminished overall life force

However, given that this study did not measure IL-6 or IL-10, it is unclear where there was also a concomitant increase in anti-inflammatory molecular factors to counteract this response