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These effects could also be partly regulated by increased levels of endocannabinoids or through TRP channels, since CBD has a relatively high affinity for TRP vanilloid receptor 1 (TRPV1), which has been shown to modulate cytokine production in microglia (Stampanoni Bassi et al., 2019)

This must be due to a lower clearance (CL) of drug B, since it was shown above that the volume of distribution is similar for both drugs

Appl Microbiol Biotechnol 104, 24112425 (2020) 3

These products are known to interfere with critical oncogenic pathways that drive tumour progression, often tipping the balance against cancer cell survival [107, 108]

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