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In female A/J mice, compared to the vehicle group, the 1.0 mg Benzo[a]pyrene treatment group shows statistically significant differences at 7 weeks, indicating that Benzo[a]pyrene-induced lung tumorigenesis is dose-dependent

The disproportionate energy needs and reliance on glucose makes the brain particularly vulnerable to disruptions in the regulation of energy metabolism [192, 193]

doi: 10.4161/cc.5.12.2820

Perez-Guisado J, Jakeman PM

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