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(2) Liquid biopsy biomarkers: development of peripheral blood or cerebrospinal fluid biomarker panels reflecting CNS pathology is needed

The pooled estimated prevalence of PACS varied by region: Asia reported the highest prevalence at 51% (95% Confidence Interval [CI]: 3765%), Europe had a prevalence of 44% (95% CI: 3256%), and the United States showed the lowest prevalence at 31% (95% CI: 2143%)