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Cobine PA, Brady DC

As observed, the trend line for the CON was consistently approximately twofolds higher than the corresponding SZ and BP trend line when considering total GSH level over the entire age distribution

This suggests that glutathione overproduction may be indispensable for the survival and proliferation of primary tumor cells, making the inhibition of glutathione production a promising therapeutic avenue for lymphoid tumors

The use of ICR mice as a preclinical model continues to provide critical insights, bridging the gap between basic research and clinical applications in AD therapy

Morphological characteristics include reducing or disappearing mitochondrial cristae, small mitochondria with condensed mitochondrial membrane densities, and outer mitochondrial membrane rupture