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There were no statistically significant differences in age between the groups initially diagnosed with or without VCD, as indicated in Table 1

Together, this evidence suggests that stress-induced BBB dysfunction associated with combat may have allowed pyridostigmine to penetrate the brain and exert central neurotoxic effects that are characteristic of Gulf War Syndrome

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer

The effects might be additive, synergistic, or potentially counteractive depending on specific circumstances

It also clearly demonstrates that the role of RABGAP1 in APP trafficking is dependent on its GAP activity, suggesting that it mediates this effect through RAB protein inactivation