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CrossRef Changes in Trace Elements During Early Stages of Chronic Kidney Disease in Type 2 Diabetic Patients Ching-Chiang Lin, Ching-Tang Shih, Chien-Hung Lee, Yeou-Lih Huang Biological Trace Element Research.2018

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The experiment was divided into a normal control group, a DSS model group, and a DSS+IGF-1 LR3 treatment group (with doses of 0.1mg/kg, 0.5mg/kg, and 1mg/kg, respectively, orally administered daily), and treated continuously for 7 days