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Dapagliflozin , a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, is primarily known for targeting renal glucose reabsorption mechanisms to manage diabetes [68]

A negative correlation was observed between amyloid depositions and glucose metabolism bilaterally in the temporal and parietal lobes, brain areas that showed glucose hypometabolism in AD subjects [49]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 135

Acknowledgements This work was supported by the Medical Research Council (Future Leaders Fellowship MR/S031812/1), by the Ministry of Education, Culture, Sports, Science and Technology of Japan (Grant-in-aid for Scientific Research on Innovative Areas 26116713 (J.-M.F.)