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In the brain tissue of the control group, the isoenzyme pattern was represented by three CAT types (Rfs 0.32, 0.58, and 0.88

The requirement of a protein pre- or post-organ and -animal development is an important distinction that is not always considered in studies involving tissue-specific knockout mouse models but potentially requires additional investigation

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doi: 10.1002/iub.2656 217 XuCYXuCXuYNDuSQDaiZHJinSQet al

As part of a continuous effort to establish effective mutation-selective inhibitory approaches for KRAS, multiple studies have highlighted isoform-dependent differences in the function and oncogenic potentials of KRAS mutations [61,62,63]