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Gallbladder problems, including gallstones or gallbladder inflammation, have been reported with tirzepatide use

For example, vitamin C supports the absorption of biotin, ensuring that this vital nutrient reaches the skin cells where its needed

In this model, it was shown that CAFs provide aspartate to cancer cells, which is taken up via the transporter SLC1A3 (also known as the excitatory amino acid transporter 1 [EAAT1]) to support nucleotide biosynthesis, while tumour cells reciprocate with glutamine-derived glutamate taken up by the CAFs through the same transporter

Their safety was confirmed in C57BL/6J mice

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