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In vitro experiments showed increased expression of antioxidant enzymes in human dermal fibroblasts (HDF) after PVDE treatment ( Centella asiatica callus bioactive metabolites clearly indicated that upregulation of cellular antioxidant enzymes seems to be the main reason for the protective effect of callus bioactive metabolites against oxidative stress (Sun et al., 2022)

[DOI] [PubMed] [Google Scholar] 69.de Moraes Crizel T., Jablonski A., de Oliveira Rios A., Rech R., Flres S.H

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