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SLC7A11 mediates the uptake of cystine and influences GSH synthesis, therefore, suppression of the SLC7A11 has also been shown to trigger ferroptosis

3.5.4.3 Prevention and intervention A key consideration is that overuse of antibiotics, particularly in childhood, can disrupt the developing microbiome and may increase susceptibility to CFS/ME later in life

These discrepancies may be explained by variations in MPTP dosages between studies or the interval of time between MPTP administration and euthanasia in the preceding study (Duan et al., 2002