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the altered activities induced ROS and malonaldehyde production, increased apoptosis, and the regulation of the mRNA expression of Bax, Bcl-2, caspase-3, caspase-9, cyt c, and p53 [166]

10.1016/S2213-2600(20)30105-3 128 SousaA.ArajoP.AzevedoJ.CruzL.FernandesI.MateusN.et al (2016)

Crosstalk between the ketogenic diet and epilepsy: from the perspective of gut microbiota

Modern clinical research has shown that saffron supplementation (typically 2050mg per day) can improve visual acuity, retinal function, and contrast sensitivity in adults with AMD.58 These effects are attributed to compounds called crocin and crocetin, which may enhance retinal blood flow and protect photoreceptor cells from oxidative stress

While apoptosis is widely recognised as the primary form of melanocyte death in vitiligo, other forms of cell death such as oxeiptosis and ferroptosis have also been considered, primarily because of their close association with oxidative stress