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We assessed the short- and long- term effects of repeated ALP exposure on behavioral responses to morphine as measured by the CPP paradigm

When the vagus nerve is compromised, it leads to severe autonomic nervous system dysfunction (dysautonomia), explaining the rapid heart rates, digestive issues, and profound cognitive impairment that define the chronic Lyme experience

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This chronic activation impairs neuronal homeostasis, worsens synaptic dysfunction, and ultimately accelerates neurodegenerative processes [113116]

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