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Furthermore, a recent clinical trial in which GDNF was infused into the putamen of PD patients via a skull-mounted transcutaneous port and four separate intraputamental infusion catheters also failed to meet its primary endpoint, as GDNF treatment did not lead to significant improvement of the motor symptoms in comparison to placebo control [45]

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We adjust the dose based on how well theyre doing and lab results

Given this understanding, the data set was split to examine the influence of the wild-type 677C T, homozygous 677TT, and heterozygous 677CT genes coding for the MTHFR enzyme, with respect to other biochemical variables of interest within the data-set

A., Portois, L