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We found that NF-B and MAPK pathways were unaffected by HK2 knockout, as determined by the levels of proteins involved in these pathways and the nuclear translocation of p65 (Supplementary Fig

Sample preparation Fish wrapped in aluminum foil were removed from the freezer and thawed to room temperature

Moreover, it remains unclear which ROS signals confer selective advantage in tumors, including H 2 O 2 -mediated signaling, lipid peroxidation, or reversible protein thiol oxidation