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According to its activity level the enzyme variants were classified in five types 23 , such as: Class 1: Deficiency of the enzyme with chronic non-spherlocytic-hemolytic anemia (CNSHA)

In the treatment of poor ovarian response (POR), paracrine factors from MenSCs modulate the local microenvironment to promote follicular development, as well as the differentiation of embryonic-like and ovarian stem cells