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For example, analyses of the structures and chemical properties of key residues in the protein crystal structures of GRK2 and GRK5 have determined the specific amino acid distribution within the GRK2/GRK5 target site [160, 161]

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Conclusion and study limitations The study demonstrates that CEdG accumulates in OSCC in association with MGO exposure and correlates with altered chromatin organization, suggesting a potential link between CEdG accumulation and tumor-associated nuclear remodeling