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Treating drug addiction and preventing relapse with ghrelin antagonists There is now substantial evidence suggesting that GHSR located in the mesolimbic dopaminergic system is associated with the amplification of reward-seeking behaviors, including those associated with drugs of abuse (Abizaid, 2009

Int Immunopharmacol (2014) 20:4653

However, in zebrafish, PS-NPs affect glucose homeostasis by increasing cortisol secretion and such alternation in cortisol levels causes behavioral changes by interfering with brain cells electrical activity that alters important molecules like neurotransmitters, enzymes, and receptors (171)

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Anagnostis P, Lambrinoudaki I, Stevenson JC, Goulis DG