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doi: 10.1016/s0015-0282(02)04948-8 7 KhosravizadehZKhodamoradiKRashidiZJahromiMShiriESalehiEet al

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extreme caloric restriction may exacerbate menstrual irregularities Micronutrient optimization: Maintain adequate iron intake, particularly if experiencing heavier menstrual bleeding Contraceptive considerations: Discuss alternative contraceptive methods with your provider, as tirzepatide may affect oral contraceptive absorption For women with pre-existing menstrual irregularities or PCOS, tirzepatide treatment may ultimately improve cycle regularity as metabolic parameters normalize

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