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Iron chelators (like deferoxamine), ROS scavengers (like N-acetylcysteine) and the canonical ferroptosis inhibitor ferrostatin-1 all attenuate this cascade, underscoring the central role of microglia-driven iron dysregulation in SCI pathology ( Ferroptotic microglia themselves amplify inflammation

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The weight gain thereafter continued to be progressively higher in HFD mice (Fig

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