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In this article, well break down the science of glutathione for skin lightening, compare IV injections to oral supplements, set realistic expectations for results, and review who might (or might not) benefit from this treatment

J Clin Biochem Nutr

Mechanistically, glutathione is understood to inhibit the enzyme tyrosinase and shift melanin production from darker eumelanin toward lighter pheomelanin, which can make skin look brighter and more even over time

Compare to healthy cells, cancer cells are characterized by increased formation of ROS and therefore to avoid ROS-induced cell death, cancer cells restore their ROS homeostasis by increasing their antioxidant capacity (Valko et al

The combined effect is that new melanin pigment isnt produced as readily, and the pigment that is produced may be of a lighter variety