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10.3389/fcimb.2023.1062963 57

hence it is expected to be a novel therapeutic tool for the metabolic syndrome

In summary, butyrate can function as a natural modulator of specific PTMs and as a drug modifier enhancing therapeutic delivery

CD271 is associated with stemness, clonogenic potential, and tissue tropism, which may have an impact on stronger tissue-repair signaling, and its reduction during passaging or expansion could lead to a decrease in the therapeutic efficacy of MSCs-derived EVs (49)