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There are two types of amplifiers which have showed promising results in pre-clinical and clinical trials, PTI-428 and PTI-CH (Proteostasis Therapeutics Inc., USA), even though they are not yet available on the market (Kym et al., 2018

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Alterations in regulatory components of NOX2 results in generation of phagocytic oxidative stress and phagocytic burst to eliminate enclosed pathogen [58]

This decision was made based on the benefits provided by the assay kit (ability to measure total GSH, free GSH, and GSSG within a single well) compared to other commercially available kits, and our prior positive results with this kit [15]

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