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doi: 10.1002/PS.2780380413 57 ShabalaS

doi: 10.1038/nm817

Contraindications and warnings Active cancer: Theoretical concern peptides promoting cell proliferation could stimulate cancer growth

Nature 463 , 676680 (2010)

In vascular smooth muscle cells from large arteries, NOX1 is required for migration, hypertrophy, and proliferation, NOX4 mediates differentiation, and NOX1 and 2 are implicated in hypertension