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Berberine affects the gut microbiome, which is increasingly recognized as an important regulator of metabolism

These readily synthesize metallothionein (MT), a protein that binds tightly to the Cd ion and allows it to be transported

10.1186/s13568-019-0808-3 252 ZhaoJ

Johansen FE, Pekna M, Norderhaug IN et al (1999) Absence of epithelial immunoglobulin A transport, with increased mucosal leakiness, in polymeric immunoglobulin receptor/secretory component-deficient mice

Thus, cytoprotective systems, such as the heat shock response, and the body antioxidant system appear to be preserved and effectively activated in response to muscle injury and inflammation induced by intense resistance training