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Magnesium is used in over 300 biological processes, including all of those involved in ATP (energy) production

John Dick's group had originally identified the AML LSCs in primary patients using serial xenotransplantation experiments in NOD/SCID immunodeficient mice and observed that LSCs reside in lineage-CD34 + CD38 cells fraction ( + cells enriches the LSCs frequency ( AML LSCs and blasts reside in bone marrow (BM) niches, where the nutrients are limited