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Using RNA sequencing (RNA-seq) combined with SNP analysis, researchers identified 61 upwardly mobile and 990 downwardly mobile mRNAs in tomato heterografts

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This, in turn, upregulates several stress-response genes, including the one encoding for nicotinamidase Pnc1, a main regulator of Sir2 activity and a well-characterized gene involved in replicative lifespan (Molina-Serrano et al., 2016)