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In the Phase III innovaTV 301 study, which enrolled more than 500 patients, Tivdak significantly boosted survival versus chemotherapy

Xu Y, Li S, Wang Y, Liu J, Mao X, Xing H, et al

Subsequently, LDL promoted the proliferation and invasion of TC cells [101]

However, as current conclusions are mainly based on correlations between microbial composition and ferroptosis rather than direct causal evidence and the lack of clinical validation, more research concerned to dynamic interactions is in need