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The animals fed a selenium-deficient diet recapitulated some of the pathological manifestations of KBD, strongly supporting the notion that selenium deficiency is critically associated with the development of this endemic arthropathy

Brain 146 , 767777 (2023)

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In practical applications, EOs are typically diluted with carrier oils (such as vegetable oils, fixed oils, or fats), cream bases, or gels, with concentrations generally ranging from 2% to 5%

In addition, some authors investigated the risk associated with serum UA levels in a large cohort of patients with tauopathies (including subgroups with progressive supranuclear palsy, AD, and frontotemporal dementia) [222]