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Description

I.ZhangW

Accepted: Published: Version of record: Issue date: DOI:

10.1016/j.plipres.2009.08.004 14

FEBS Lett 593:21392150 Shitara Y, Nakamichi N, Norioka M, Shima H, Kato Y, Horie T (2013) Role of organic cation/carnitine transporter 1 in uptake of phenformin and inhibitory effect on complex I respiration in mitochondria

What they found: Darkening of existing nevi in 85 % of patients New nevi in 30 % Atypical features on dermatoscopy in 40 % Two cases of malignant melanoma in the followed cohort No evidence of a causal relationship, but associative correlation Why it matters: These are the most serious published safety data for Melanotan II