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Extrapolation of these findings to the context of Down syndrome Our results, supported by others in mouse models ( DYRK1A and CBS have additive effects and that CBS expression and/or activity is increased following DYRK1A overexpression

For GST pulldowns, researchers usually first purify the GST-fusion version of their protein of interest

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Alternatively, and more recently, gold-based fluorescent nanoclusters (AuNCs) attracted a significant interest as an ultrasmall inorganic nanoprobes (core size less than 2 nm) with stable photoluminescence properties 13,14,15,16

doi: 10.1016/j.arr.2005.02.005 179 MahnA.CastilloA