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In the FDAs September 27, 2024 update, BPC-157 and Thymosin Beta-4, Fragment (LKKTETQ) appear under Category 2

IGF-1 LR3 functions through direct, sustained agonism of the IGF-1 receptor (IGF-1R), a receptor tyrosine kinase, activating the same downstream intracellular signalling cascades as native IGF-1 but with substantially reduced IGFBP-mediated attenuation and a far longer biological activity window

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Scientific Panel on Dietetic Products, Nutrition and Allergies Unit BACKGROUND Consolidated list of Article 13 health claim List of references received by EFSA Part 4 IDs 3001 4262 (only for claims which passed the EFSA screening) Parma, 21 September 2009 In accordance with Article 13 of Regulation (EC) No 1924/2006 1 Member States had provided the European Commission with lists of claims accompanied by the conditions applying to them and by references to the relevant scientific justification by 31 January 2008