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Moreover, both additional akt1 mRNA or activation of mTOR reversed the effects of sulindac, further supporting the hypothesis that sulindac acts by inhibiting the PI3K/AKT/mTOR pathway in the autophagic cell death process of zebrafish neurons

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Current study methods provide an increasing amount of data on the genetics of sporadic PAs, as seen in recent reports on the increasingly better-understood genetics of corticotropic PAs