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By reducing the activity of macrophages and impeding the infiltration of inflammatory elements into the brain parenchyma, bevacizumab contributes to a neuroprotective milieu (Genovese and Impellizzeri 2022)

thaliana , six isoforms of MDHAR are present among which two are peroxisomal, two are cytosolic and one is dually targeted chloroplastic/mitochondrial isoform (Lisenbee et al., 2005) (Table 2)

Following the stimulation of cells with growth factors, the phosphorylation of DRP1 at S616 by ERK drives mitochondrial fission, which can be blocked by the application of MAPK inhibitors (Kashatus et al., 2015

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