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The baseline expression of human epidermal growth factor receptor 2 (HER2) in healthy tissues, a well-characterized therapeutic target for cancer therapy 8 , has led to lethal cardiopulmonary toxicity in patients with colorectal cancer who were pretreated with HER2-based chimeric antigen receptor T cell therapy 9

The procedure is quick and requires only local anesthesia to keep you comfortable so you can resume your normal routine soon after treatment

doi:10.1093/toxsci/kfi057

Please contact your local hospital, clinic or phlebotomy service for lab specimen collection

In such a case, the vial must be discarded immediately