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In the case of thin, crepey skin with many small wrinkles, the skin lacks its youthful support of collagen - and that can be corrected with collagen-induction therapies (there are non-invasive, non-surgical, and surgical options - generally speaking there is a trade-off between less invasive procedures needing more treatment sessions to achieve the same result as a more invasive procedure within this category of treatment)

doi: 10.1111/vru.12807

The enrichment of primary bile acids was more obvious in CD

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