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The role of mitochondrial dysfunction in sepsis-induced multi-organ failure

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Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression

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In the second part of the study, we compared the effects of long-term (four-day) exposure to DMSO on yeast cells with varying antioxidant system efficiency (wild type cells and sod1 and sod2 mutants) and with varying energy metabolism (aerobic, mixed respiratory-fermentative and fully fermentative metabolism) to identify cellular targets which are particularly sensitive to this xenobiotic