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doi: 10.1038/s41564-017-0089-z, 89 Shen-GuntherJ.XiaQ.CaiH.WangY

For example, ACSL4 preferentially showed high expression in ER-negative BC cell lines, such as human breast cancer cells (MDA-MB-231), but low expression in ER-positive BC cell lines, such as breast epithelial cells (MCF-7)

As it oxidizes, a noncovalently bound FAD is reduced, and electrons are transferred to coenzyme Q, contributing to the electron transport chain and ATP production