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172 The expression of itaconate, a mitochondrial metabolite with antimicrobial and antiinflammatory functions that accumulates when the Krebs cycle is disrupted, is upregulated in murine models of asthma 173 where it suppresses both proinflammatory (M1) and alternatively activated (M2) macrophages

Lima et al

Andrews, D

The results of the current investigation demonstrated that significant increases in MDA and decreases in TAC, SOD, CAT, and GSH were seen in DOX-induced ovarian oxidative stress