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Generally, CAMKK2 has been identified as the hypothalamic AMPK kinase that transduces Ca2+-mediated ghrelin signaling, inhibiting selectively hypothalamic AMPK and NPYs downstream orexigenic effect

Glial cells, including microglia, astrocytes, and oligodendrocytes, serve as supportive cells in the central nervous system (CNS), but their abnormal activation can lead to DA neuron death and ferroptosis

The tumor suppressor gene, WT1, is expressed in both human and mouse hematopoietic tissues

ZhangYZhouXWangZWuMZhangWZhangZet al

To summarise, we have shown that the interactions of the centrosomal protein CEP192 with Aurora-A compete with spindle microtubule-associated TACC3 and TPX2 binding, and validated the crystal structure using site-specific mutagenesis