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doi: 10.1111/j.1365-2036.2007.03413.x

These studies used doses ranging from 1 mg per day to 30 mg per day administered through various routes (subcutaneous, oral, and intranasal)

This 48-week, randomized, double-blind, placebo-controlled study enrolled 338 adults with obesity or overweight with at least one weight-related comorbidity