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A competitive binding assay was utilized to determine the K i of each compound similar to previous reports 55,56

Kuffler and Foy, 2020)

False-positive result: False-positive results are reported in diabetes mellitus, adrenal insufficiency, thyroid diseases, and various gastric abnormalities

The Y-maze spontaneous alternation test, which can be used longitudinally to assess working memory in the same cohort of mice [89,90,91], was performed at 6, 15, and 21 months of age