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111 Understanding how genetic and epigenetic, neurologic, hormonal, and immune mechanisms contribute to the experience of pain may help patients reconceptualize their condition, feel less anxious, and feel more empowered to make changes that can improve their outcomes

In dierstudies wordt het eenmaal daags subcutaan, intraperitoneaal of oraal toegediend (maagstabiel)

Frequency depends on deficiency severity

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If you have other close relatives with the disease, youre more likely to be at risk