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For labs making oxidative stress, ferroptosis, metabolic damage or signal transduction models, CBS activity can provide the critical distinction between upregulation of interest and upregulation of artifact to separate out expression changes from functional changes

This mainly involves knocking out virulence genes or integrating exogenous functional modules to give them stable drug synthesis and regulation capabilities

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FASEB Bioadv 5(6):233250

Published research has quantified this effect directly: at concentrations of 12 M, only 1020% of expected peptide content was recovered from standard borosilicate glass vials and polypropylene tubes after incubation, while low-binding tubes showed significantly better recovery