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Targeting PRLM-driven pathways has emerged as a promising therapeutic strategy for diverse non-resolving chronic inflammatory diseases (NCDs), including cardiovascular disease, neurodegenerative disorders, metabolic syndrome, autoimmune disorders, and cancer [3]

( g ) HTML:TML ratio was assessed in FT282-CCNE1 cells treated with the IDH1 inhibitor and supplemented with KG (n = 8 technical replicates representative from 2 independent experiments)