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Positional cloning of the mouse obese gene and its human homologue

Journal of internal medicine

Where the evidence was convincing, we changed what we do

Given the importance of the cofactor in energy metabolism, NAD + is especially important in mitochondrial function, and in fact both NAD + and mitochondria are concentrated in energetically demanding tissues 1012

Neurological problems : Some people with coeliac disease may experience neurological symptoms, such as peripheral neuropathy, ataxia (impaired coordination), and epilepsy