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In this genetic strain, the HR birds were also characterized by lower Total Antioxidant Status ( 8%) and tocopherols concentration ( 35%), but a higher value of hydrogen peroxide (+ 22%)

And phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) signal transduction pathways are also likely to regulate FASN expression (63, 64)

Interestingly, most lung cancers occurring in patients with reported passive exposure to tobacco smoke also do not contain these signatures 7,78