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Educate the patient on the importance of risk factor control

Nat Rev Mol Cell Biol 8 , 729740, (2007)

Patients looking to achieve optimal hydration will notice immediate improvements in symptoms caused by a lack of electrolytes and/or certain vitamins

Your healthcare practitioner may recommend a folate or L-methylfolate supplement

In contrast, treatment with natural compounds would counteract these effects by inducing the Nrf2/KEAP1 signaling pathway and reinforcing antioxidant defenses